Track and block meth precursors in real-time with the National Precursor Log Exchange

The National Precursor Log Exchange (NPLEx) is a real-time electronic logging system used by pharmacies and law enforcement to track sales of over-the-counter (OTC) cold and allergy medications containing precursors to the illegal drug, methamphetamine.

Start Tracking Meth Precursors

Benefits for Pharmacies

NPLEx is a real-time electronic logging and compliance system that tracks sales of over-the-counter (OTC) cold and allergy medications containing pseudoephedrine (PSE).

eliminate paper logs

Eliminate Manual Paper Logs

Pharmacies can easily enter transactions through either a Web portal or Web service, eliminating bulky paper logs, and speeding up transaction times.

track and block overages

Track and Block Overrages

Not only does NPLEx track the amount of PSE individuals purchase, it automatically blocks the sale of PSE in excess of state or local limits.

POS integration

Integrate with your POS

NPLEx can be easily integrated into your existing POS, or is also available 24/7 on our secure web portal, to make your transition nearly effortless.

NPLEx States


"NPLEx has been a pleasantly easy tool for documenting PSE sales. We no longer need to be concerned about whether the customer has been buying PSE from other sources that day. The scanner has made the process very quick and easy and the support staff have been very helpful in getting my system up and running. Yesterday we were having problems logging on and I called the help desk. After a few minutes trying to walk me through the problem, the representative simply logged into my system and had me up and running in just a few minutes. Great support staff, thanks."

Phil Colbert | Owner and PIC | Phil's Pharmacy | Iowa

Benefits for Law Enforcement

Fight meth labs with the help of NPLEx. Get real-time alerts when persons of interest attempt to purchase PSE, or search our secure site to find known suspects.


Easily Accessible

NPLEx is available 24/7 via a secure website, accessible from a device with internet connectivity.

overage alerts

Overrage Alerts

NPLEx provides automated tools that give law enforcement the ability to "watch" suspicious buying patterns.

real time monitoring

Real-Time Monitoring

Know a suspect has just entered a store? NPLEx Store Feed allows up to three stores to be selected to watch in real time.


"In the year 2009, our Task Force has successfully indicted 54 individuals through the United States Attorney's Office, for the charge of conspiracy to purchase pseudoephedrine with the intent to manufacture methamphetamine. This accounts for 28% of the federal drug indictments for the Eastern District of Missouri. The St. Louis County Police Department's Methamphetamine Precursor Diversion Task Force would not have been this successful without the assistance of our real time precursor tracking system."

Sergeant T.M. | St. Louis Police MPDTF | St. Louis, Missouri